Description

Ethanone, 2,2,2-Trifluoro-1-(3-Hydroxyphenyl)- (9Ci) is a specialized trifluoromethyl ketone derivative that serves as a high-value synthetic intermediate. Its unique structure, featuring both a phenolic hydroxyl group and a trifluoroacetyl moiety, makes it a versatile building block for constructing complex molecules with enhanced properties. This compound is primarily sought after by research and development teams in the pharmaceutical and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, contributing to the molecular framework of dyes and charge-transport layers.
• Polymer Modification: Employed to introduce fluorinated segments into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Chemical Synthesis Reagent: Acts as a versatile reagent in organic synthesis for introducing the 2,2,2-trifluoro-1-arylethanone functional group into target molecules.
• Bioconjugation & Probe Development: Useful in biochemical research for creating fluorescent probes or affinity labels due to its reactive ketone and phenolic groups.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(3-Hydroxyphenyl)- (9Ci)
CAS No.	326897-98-7
Molecular Formula	C9H5F3O2
Molecular Weight	202.13 g/mol
Synonyms	3'-Hydroxy-2,2,2-trifluoroacetophenone; 1-(3-Hydroxyphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(3-hydroxyphenyl)ethanone; 3-Hydroxy-α,α,α-trifluoroacetophenone; 3-Hydroxyphenyl trifluoromethyl ketone; m-Hydroxy-α,α,α-trifluoroacetophenone; 3'-Hydroxy-α,α,α-trifluoroacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(3-Hydroxyphenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.