Description

5,11,17,23-Tetrakis-Mercaptomethyl-25,26,27,28-Tetrapropoxycalix[4]arene is a sophisticated, functionalized calixarene derivative featuring four strategically positioned thiol (-SH) groups. This molecular architecture makes it an exceptionally versatile building block for supramolecular chemistry and advanced material science. It is primarily sought by researchers and product developers in the fields of chemical sensing, catalysis, and nanotechnology for constructing complex molecular scaffolds and selective host-guest systems.

Application

• Molecular Recognition & Sensing: Acts as a selective host for metal ions and organic molecules in the development of chemical sensors and extraction agents.
• Catalysis & Ligand Design: Serves as a multidentate ligand for transition metals, enabling the creation of novel catalysts for organic synthesis.
• Nanomaterial Fabrication: Used as a functional anchor or stabilizer for nanoparticles (e.g., gold, silver) due to its strong thiol-metal interactions.
• Surface Modification: Employed to create self-assembled monolayers (SAMs) on metal surfaces for controlling surface properties and biocompatibility.
• Polymer & Dendrimer Synthesis: Functions as a core unit or cross-linker in the synthesis of polymers and dendrimers with tailored properties.
• Pharmaceutical Research: Investigated for potential applications in drug delivery systems and as a scaffold for bioactive compound design.

Basic Information

Product Name	5,11,17,23-Tetrakis-Mercaptomethyl-25,26,27,28-Tetrapropoxycalix[4]arene
CAS No.	325776-17-8
Molecular Formula	C52H68O4S4
Molecular Weight	909.33 g/mol
Synonyms	Calix[4]arene-tetrathiol; Tetrapropoxy-tetrakis(mercaptomethyl)calix[4]arene; 25,26,27,28-Tetrapropoxycalix[4]arene-5,11,17,23-tetrathiol; p-tert-Butylcalix[4]arene-tetrathiol derivative; Thiolated calixarene; Mercaptocalixarene; Tetrathiol Calix[4]arene
EINECS	Contact for details

Quality Control

Every batch of our 5,11,17,23-Tetrakis-Mercaptomethyl-25,26,27,28-Tetrapropoxycalix[4]arene undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the exacting standards of research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation of the thiol groups and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Thiol Titration)	≥ 90.0%
Solubility	Soluble in THF, DMF, DMSO; Slightly soluble in chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.