Description

L-Threo-Pentonic Acid, 2,3-Dideoxy-2-(1-Methylethyl)-, γ-Lactone (9Ci) is a specialized chiral lactone derivative with a defined stereochemistry, serving as a high-value synthetic intermediate. Its core value lies in providing a rigid, functionalized scaffold for constructing complex molecules in advanced pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in the synthesis of nucleoside analogs, enzyme inhibitors, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Agrochemical Research: Used in developing advanced pesticides and herbicides with specific chiral activity.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective organic reactions.
• Biochemical Research: Potential precursor for modified sugars or enzyme inhibitor studies.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals requiring high purity and defined stereochemistry.

Basic Information

Product Name	L-Threo-Pentonic Acid, 2,3-Dideoxy-2-(1-Methylethyl)-, γ-Lactone (9Ci)
CAS No.	325740-73-6
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	2,3-Dideoxy-2-isopropyl-L-threo-pentono-1,4-lactone; (3R,4S)-4-(Hydroxymethyl)-3-isopropyl-dihydrofuran-2(3H)-one; L-threo-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, γ-lactone; Isopropyl-substituted L-threo-pentono-1,4-lactone; 325740-73-6; 2-Isopropyl-2,3-dideoxy-L-threo-pentono-1,4-lactone
EINECS	Contact for details

Quality Control

Our L-Threo-Pentonic Acid, 2,3-Dideoxy-2-(1-Methylethyl)-, γ-Lactone (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, purity, and consistency for your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.