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4-(N,n-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester CAS NO 325142-99-2


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CAS No.:325142-99-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(N,N-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is a sophisticated organoboron building block, specifically a protected boronic acid derivative. This compound is critical for enabling complex cross-coupling reactions, such as the Suzuki-Miyaura reaction, with enhanced stability and handling properties compared to its free acid form. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl coupling steps.
  • Material Science Research: Employed in the creation of organic electronic materials, polymers, and liquid crystals where precise aromatic structures are needed.
  • Chemical Biology & Probe Development: Serves as a precursor for bioconjugation reagents and molecular probes used in diagnostic and imaging applications.
  • Process Chemistry & Scale-up: The pinacol ester's stability makes it suitable for optimized, large-scale manufacturing processes in fine chemical production.
  • Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and catalysis research.

Basic Information

Product Name 4-(N,N-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester
CAS No. 325142-99-2
Molecular Formula C17H26BNO3
Molecular Weight 303.21 g/mol
Synonyms 4-(Diethylcarbamoyl)phenylboronic acid pinacol ester; [4-(Diethylcarbamoyl)phenyl]boronic acid pinacol ester; B-[4-(Diethylaminocarbonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Carbamoylphenylboronic Acid Pinacol Ester (Diethyl derivative); Pinacol [4-(N,N-Diethylaminocarbonyl)phenyl]boronate; 4-(Diethylcarbamoyl)benzeneboronic Acid Pinacol Ester
EINECS Contact for details

Quality Control

Our 4-(N,N-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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