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4-(N,n-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester CAS NO 325142-99-2
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CAS No.:325142-99-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-(N,N-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is a sophisticated organoboron building block, specifically a protected boronic acid derivative. This compound is critical for enabling complex cross-coupling reactions, such as the Suzuki-Miyaura reaction, with enhanced stability and handling properties compared to its free acid form. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl coupling steps.
- Material Science Research: Employed in the creation of organic electronic materials, polymers, and liquid crystals where precise aromatic structures are needed.
- Chemical Biology & Probe Development: Serves as a precursor for bioconjugation reagents and molecular probes used in diagnostic and imaging applications.
- Process Chemistry & Scale-up: The pinacol ester's stability makes it suitable for optimized, large-scale manufacturing processes in fine chemical production.
- Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and catalysis research.
Basic Information
| Product Name | 4-(N,N-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester |
| CAS No. | 325142-99-2 |
| Molecular Formula | C17H26BNO3 |
| Molecular Weight | 303.21 g/mol |
| Synonyms | 4-(Diethylcarbamoyl)phenylboronic acid pinacol ester; [4-(Diethylcarbamoyl)phenyl]boronic acid pinacol ester; B-[4-(Diethylaminocarbonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Carbamoylphenylboronic Acid Pinacol Ester (Diethyl derivative); Pinacol [4-(N,N-Diethylaminocarbonyl)phenyl]boronate; 4-(Diethylcarbamoyl)benzeneboronic Acid Pinacol Ester |
| EINECS | Contact for details |
Quality Control
Our 4-(N,N-Diethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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