Description

2-(3-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron reagent, specifically a pinacol boronic ester. This compound is a critical synthetic intermediate valued for its stability and reactivity in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for complex molecule synthesis. The CAS number for this product is 325142-89-0.

Application

This versatile boronic ester is a key reagent in modern synthetic chemistry, enabling the construction of complex molecular architectures. Its primary applications include:

• Suzuki-Miyaura Cross-Coupling Reactions: As a stable boronic ester precursor for forming carbon-carbon bonds, crucial in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Serving as a building block for active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides.
• Material Science: A precursor for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of probes and tool compounds for biological target validation.
• Fine Chemical Production: Enabling the scalable synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-(3-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	325142-89-0
Molecular Formula	C15H23BO2
Molecular Weight	246.15 g/mol
Synonyms	3-Isopropylbenzeneboronic acid pinacol ester; (3-Isopropylphenyl)boronic acid pinacol ester; 1-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; m-Isopropylphenylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cumene; Boronic acid, B-(3-isopropylphenyl)-, 1,1-dimethylethyl ester; Pinacol (3-isopropylphenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-(3-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.