Description

4,4,5,5-Tetramethyl-2-(Perfluorophenyl)-1,3,2-Dioxaborolane is a high-purity, specialized organoboron reagent featuring a perfluorinated aromatic ring. This compound is a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions to introduce fluorinated aromatic systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable fluorinated intermediates for developing new active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl bonds with perfluorophenyl groups, crucial in pharmaceutical and material science R&D.
• Pharmaceutical Intermediate Synthesis: Used in the development of active pharmaceutical ingredients (APIs) where fluorinated aromatic moieties enhance metabolic stability and bioavailability.
• Agrochemical Compound Development: Serves as a building block for novel herbicides, fungicides, and insecticides that leverage fluorine's unique properties.
• Advanced Material Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials for OLEDs and semiconductors.
• Medicinal Chemistry & Drug Discovery: Facilitates the rapid exploration of chemical space in lead optimization programs through efficient library synthesis.
• Catalyst and Ligand Development: Used to create novel fluorinated ligands for transition metal catalysis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(Perfluorophenyl)-1,3,2-Dioxaborolane
CAS No.	325142-81-2
Molecular Formula	C12H12BF5O2
Molecular Weight	294.03 g/mol
Synonyms	2-(Perfluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pentafluorophenylpinacolborane; Perfluorophenylboronic Acid Pinacol Ester; C6F5Bpin; Pinacol Perfluorophenylboronate; (Perfluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(Pentafluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(Perfluorophenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms
19F NMR	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.