Description

2-Acetylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its stability for efficient coupling steps.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel palladium ligands and other organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	2-Acetylphenylboronic Acid Pinacol Ester
CAS No.	325141-75-1
Molecular Formula	C14H19BO3
Molecular Weight	246.11 g/mol
Synonyms	1-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-one; 2-Acetylbenzeneboronic Acid Pinacol Ester; (2-Acetylphenyl)boronic Acid Pinacol Ester; 2-Acetylphenylboronic Acid Neopentyl Glycol Ester (common alternative); 2-Acetylphenyl-Bpin; B-(2-Acetylphenyl)pinacolboronate; Pinacol (2-Acetylphenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-Acetylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.