Description

5-Chloro-2-Ethoxy-4-Tosylthiazole is a high-value, multi-functional heterocyclic building block with a unique molecular architecture. This compound is critical for synthetic chemists developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex thiazole-based scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as organic semiconductors or light-emitting materials.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a core structure for designing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific thiazole derivative.

Basic Information

Product Name	5-Chloro-2-Ethoxy-4-Tosylthiazole
CAS No.	324579-75-1
Molecular Formula	C12H12ClNO3S2
Molecular Weight	317.81 g/mol
Synonyms	4-Methylbenzenesulfonic Acid 5-Chloro-2-ethoxy-4-thiazolyl Ester; 5-Chloro-2-ethoxy-4-(4-methylphenyl)sulfonylthiazole; 5-Chloro-2-ethoxy-4-(p-toluenesulfonyl)thiazole; 5-Chloro-2-ethoxy-4-tosyl-thiazole; 324579-75-1; Thiazole, 5-chloro-2-ethoxy-4-[(4-methylphenyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Ethoxy-4-Tosylthiazole is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.