Description

Ethyl 3-(Tetrahydrofuran-3-Yl)-3-Oxopropanoate is a high-purity, versatile β-keto ester derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a tetrahydrofuran ring and a reactive keto-ester moiety, makes it an invaluable intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those containing fused heterocyclic systems for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create targeted bioactive compounds.
• Fine Chemical Building Block: Employed in multi-step organic synthesis for producing specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: Serves as a versatile starting material in method development and discovery chemistry for creating new chemical entities.
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialized polymers with tailored properties.

Basic Information

Product Name	Ethyl 3-(Tetrahydrofuran-3-Yl)-3-Oxopropanoate
CAS No.	324570-25-4
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	Ethyl 3-(oxolan-3-yl)-3-oxopropanoate; 3-Oxobutanoic acid, 3-(tetrahydro-3-furanyl)-, ethyl ester; Ethyl 3-(3-tetrahydrofuranyl)-3-oxopropionate; 3-(Tetrahydrofuran-3-yl)-3-oxopropionic acid ethyl ester; Ethyl 3-oxo-3-(tetrahydrofuran-3-yl)propanoate; Acetoacetic acid, 3-(tetrahydro-3-furanyl)-, ethyl ester; Ethyl 3-(tetrahydrofuran-3-carbonyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Tetrahydrofuran-3-Yl)-3-Oxopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, organic solvents, and strong oxidizing agents. Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep the container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.