Description

Diisopropyl 5-Methyl-2-Thiazoleboronate Lithium Isopropoxide Salt is a high-value organoboron reagent, specifically a lithium isopropoxide complex of a thiazole-substituted boronic ester. This compound is critical for enabling efficient and selective cross-coupling reactions, particularly in the synthesis of complex heterocyclic molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boron-containing coupling partner for the synthesis of biaryl and heteroaryl compounds.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) containing the 5-methyl-2-thiazole moiety.
• Agrochemical Research: Employed in the creation of novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Precursor: Acts as a building block for organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the development of molecular probes and diagnostic agents targeting specific biological pathways.
• Process Chemistry Optimization: Provides a stable, soluble alternative to boronic acids for scalable manufacturing processes.

Basic Information

Product Name	Diisopropyl 5-Methyl-2-Thiazoleboronate Lithium Isopropoxide Salt
CAS No.	324560-66-9
Molecular Formula	C12H21BLiNO3S
Molecular Weight	269.13 g/mol
Synonyms	Lithium Diisopropyl (5-Methyl-2-thiazolyl)boronate Isopropoxide Complex; 5-Methyl-2-thiazoleboronic Acid Diisopropyl Ester Lithium Isopropoxide Salt; (5-Methyl-2-thiazolyl)boronic Acid Diisopropyl Ester Lithium Isopropoxide Adduct; Diisopropyl (5-Methylthiazol-2-yl)boronate Lithium Isopropoxide; Boronic acid, B-(5-methyl-2-thiazolyl)-, diisopropyl ester, lithium salt (1:1), compd. with 2-propanol (1:1); 324560-66-9; Lithium Isopropoxide Adduct of Diisopropyl 5-Methyl-2-thiazoleboronate
EINECS	Contact for details

Quality Control

Our Diisopropyl 5-Methyl-2-Thiazoleboronate Lithium Isopropoxide Salt is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen). Due to its hygroscopic nature, the container should only be opened in a moisture-controlled environment, such as a glovebox or under a continuous dry gas purge.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (NMR)	≥ 90.0% w/w
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.