Description

(R)-Boroalg(+)-Pinanediol CAS NO 323197-73-5 is a high-purity, chiral boronic ester derivative of pinanediol, serving as a critical chiral auxiliary and building block in asymmetric synthesis. Its primary value lies in enabling the stereoselective formation of carbon-carbon bonds, a cornerstone of modern pharmaceutical and fine chemical manufacturing. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require precise control over molecular chirality to develop new active ingredients and functional molecules.

Application

• Asymmetric Suzuki-Miyaura Cross-Coupling Reactions: Acts as a chiral boron reagent for the stereocontrolled synthesis of biaryl and other complex molecular architectures.
• Pharmaceutical Intermediate Synthesis: A key precursor in the multi-step synthesis of chiral active pharmaceutical ingredients (APIs) targeting central nervous system, oncology, and metabolic diseases.
• Agrochemical Research & Development: Used to construct chiral centers in novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Material Science: Employed in the research of chiral polymers and organic electronic materials with specific optical properties.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and scaling up chiral transformations.

Basic Information

Product Name	(R)-Boroalg(+)-Pinanediol
CAS No.	323197-73-5
Molecular Formula	C₁₆H₂₇BO₂
Molecular Weight	262.20 g/mol
Synonyms	(+)-Pinanediol (R)-Boroalginate; (R)-4,4,5,5-Tetramethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane (Pinanediol ester); (R)-Boroalg Pinanediol Ester; (R)-Pinanediol Boronic Ester of Boroalgic Acid; (R)-Boroalg Pinacol Ester Analog; (1R,2R,3S,5R)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol (R)-Boroalg Ester
EINECS	Contact for details

Quality Control

Our (R)-Boroalg(+)-Pinanediol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, NMR (¹H, ¹³C, ¹¹B), and GC/MS, to ensure high enantiomeric excess (ee) and chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliable performance and batch-to-batch consistency for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (argon or nitrogen) to maintain stability and purity. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.