Description

Ethyl 2,2-Difluoro-3-Hydroxybutanoate is a high-value fluorinated organic building block, a key intermediate in the synthesis of complex molecules. Its unique structure, featuring both fluorine atoms and a hydroxyl group, makes it a versatile synthon for introducing fluorinated motifs, which are crucial for modulating the physical, chemical, and biological properties of target compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine substitution enhances efficacy and environmental stability.
• Material Science Precursor: Serves as a monomer or intermediate for developing specialty polymers and advanced materials with tailored surface properties and stability.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex organic molecules, leveraging its chiral center for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorine substitution on molecular conformation and reactivity in medicinal chemistry.

Basic Information

Product Name	Ethyl 2,2-Difluoro-3-Hydroxybutanoate
CAS No.	321942-91-0
Molecular Formula	C6H10F2O3
Molecular Weight	168.14 g/mol
Synonyms	Ethyl 2,2-Difluoro-3-hydroxybutyrate; 2,2-Difluoro-3-hydroxybutanoic Acid Ethyl Ester; 3-Hydroxy-2,2-difluorobutanoic Acid Ethyl Ester; Butanoic acid, 2,2-difluoro-3-hydroxy-, ethyl ester; Ethyl 3-Hydroxy-2,2-difluorobutanoate
EINECS	Contact for details

Quality Control

We supply Ethyl 2,2-Difluoro-3-Hydroxybutanoate in high-purity grades suitable for research and industrial synthesis. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the product at 2-8°C under an inert atmosphere is recommended to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.