Description

1-Azetidineacetic Acid, 3-[[(1Z)-3-Methoxy-1-Methyl-3-Oxo-1-Propenyl]Amino]-2-[(1E)-2-(2-Methoxyphenyl)Ethenyl]-4-Oxo-Methyl Ester is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. This compound is valued for its unique azetidine core and complex functionalization, making it a critical intermediate for research and development in pharmaceutical chemistry. It is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting complex biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Organic Synthesis: Acts as a versatile intermediate for constructing complex heterocyclic and peptidomimetic frameworks in academic and industrial laboratories.
• Bioconjugation & Probe Development: Potential use in creating specialized probes or conjugates for biochemical and diagnostic research due to its reactive handles.

Basic Information

Product Name	1-Azetidineacetic Acid, 3-[[(1Z)-3-Methoxy-1-Methyl-3-Oxo-1-Propenyl]Amino]-2-[(1E)-2-(2-Methoxyphenyl)Ethenyl]-4-Oxo-Methyl Ester
CAS No.	321870-36-4
Molecular Formula	C21H24N2O6
Molecular Weight	400.43 g/mol
Synonyms	Methyl 3-[[(1Z)-3-methoxy-1-methyl-3-oxo-1-propen-1-yl]amino]-2-[(1E)-2-(2-methoxyphenyl)ethenyl]-4-oxo-1-azetidineacetate; 1-Azetidineacetic acid, 3-[(3-methoxy-1-methyl-3-oxo-1-propen-1-yl)amino]-2-[2-(2-methoxyphenyl)ethenyl]-4-oxo-, methyl ester, (2E,3Z)-; (2E,3Z)-Methyl 3-[(3-methoxy-1-methyl-3-oxoprop-1-en-1-yl)amino]-2-[2-(2-methoxyphenyl)vinyl]-4-oxoazetidine-1-acetate; AZD-1 Intermediate; Complex Azetidine Ester Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality is verified through advanced analytical techniques including HPLC, NMR, and MS, meeting the exacting standards required for pharmaceutical R&D and process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate and stored away from oxidizing agents. Keep container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.