Description

Dispiro[2.0.2.1]Heptane-1-Methanol, 7,7-Difluoro-, (1S,3S)- (9Ci) is a high-purity, stereochemically defined organic building block featuring a unique dispirocyclic core. This compound is valued for its rigid, three-dimensional structure and the presence of fluorine atoms, which are critical for modulating the physicochemical properties of advanced materials and pharmaceuticals. It serves as a sophisticated chiral synthon for researchers and process chemists in pharmaceutical development, agrochemical research, and materials science, enabling the creation of novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms and rigid structure can improve biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Science: Incorporated into specialty polymers and liquid crystals to impart specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems due to its potential for bioorthogonal labeling.

Basic Information

Product Name	Dispiro[2.0.2.1]Heptane-1-Methanol, 7,7-Difluoro-, (1S,3S)- (9Ci)
CAS No.	321857-22-1
Molecular Formula	C8H10F2O
Molecular Weight	160.16 g/mol
Synonyms	(1S,3S)-7,7-Difluorodispiro[2.0.2.1]heptane-1-methanol; (1S,3S)-7,7-Difluoro-1-(hydroxymethyl)dispiro[2.0.2.1]heptane; 7,7-Difluorodispiro[2.0.2.1]heptane-1-methanol, (1S,3S)-; (1S,3S)-Dispiro[2.0.2.1]heptane-1-methanol, 7,7-difluoro-; 321857-22-1; Difluorodispiroheptanemethanol (stereoisomer)
EINECS	Contact for details

Quality Control

Our production of Dispiro[2.0.2.1]Heptane-1-Methanol, 7,7-Difluoro-, (1S,3S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.