Description

Pyrimidine-5-Boronic Acid Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel pyrimidine-based drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Enables the creation of organic electronic materials, such as OLED emitters and charge-transport layers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel organometallic catalysts and chiral ligands.
• Academic & Contract Research: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	Pyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	321724-19-0
Molecular Formula	C10H15BN2O2
Molecular Weight	206.06 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; Pyrimidin-5-ylboronic Acid Pinacol Ester; 5-Pyrimidineboronic Acid Pinacol Ester; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 321724-19-0; Pyrimidine-5-boronic Acid Neopentyl Glycol Ester (common alternative); 5-Boronopyrimidine Pinacol Ester
EINECS	Contact for details

Quality Control

Our Pyrimidine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.