Description

4-Acetamido-2-Methylbenzonitrile is a high-purity organic intermediate characterized by its benzonitrile core functionalized with acetamido and methyl groups. This compound matters as a versatile building block for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on the creation of new active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its nitrile functionality.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for metal-catalyzed reactions or as a scaffold for catalyst design.
• Dye and Pigment Intermediate: Acts as a starting material for the synthesis of specialized dyes and organic pigments.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and cyanation reactions.

Basic Information

Product Name	4-Acetamido-2-Methylbenzonitrile
CAS No.	321162-59-8
Molecular Formula	C10H10N2O
Molecular Weight	174.20 g/mol
Synonyms	N-(4-Cyano-3-methylphenyl)acetamide; 4-Acetamido-o-tolunitrile; 2-Methyl-4-acetamidobenzonitrile; 4-Acetylamino-2-methylbenzonitrile; Acetamide, N-(4-cyano-3-methylphenyl)-; 4-(Acetylamino)-2-methylbenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Acetamido-2-Methylbenzonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.