Description

2-(4-Methylpiperazin-1-yl)thiazole-5-carboxaldehyde is a versatile heterocyclic building block featuring a thiazole core substituted with a formyl group and a methylpiperazine moiety. This compound is of significant value in medicinal chemistry and pharmaceutical research as a key intermediate for the synthesis of novel drug candidates. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of kinase inhibitors, antimicrobial agents, and other bioactive heterocycles.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: The aldehyde functional group allows for conjugation, making it useful for creating labeled compounds or affinity probes.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of complex organic molecules in contract research and manufacturing.

Basic Information

Product Name	2-(4-Methylpiperazin-1-yl)thiazole-5-carboxaldehyde
CAS No.	320423-50-5
Molecular Formula	C9H13N3OS
Molecular Weight	211.28 g/mol
Synonyms	2-(4-Methyl-1-piperazinyl)-5-thiazolecarboxaldehyde; 5-Formyl-2-(4-methylpiperazin-1-yl)thiazole; 2-(4-Methylpiperazin-1-yl)-1,3-thiazole-5-carbaldehyde; 320423-50-5; Thiazole-5-carboxaldehyde, 2-(4-methyl-1-piperazinyl)-; 2-(4-Methylpiperazino)thiazole-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazin-1-yl)thiazole-5-carboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider an inert atmosphere. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.