Description

(R)-Boroabu-(+)-Pinanediol-Hcl CAS NO 319009-92-2 is a high-purity, chiral organoboron reagent, specifically the hydrochloride salt of a pinanediol-protected boronic acid derivative. This compound is a critical building block in asymmetric synthesis, enabling the stereoselective formation of carbon-carbon bonds. It is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing chiral biaryl and other complex molecular architectures with high enantiomeric purity.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of chiral drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Catalyst and Ligand Development: Serves as a precursor for novel chiral catalysts and ligands used in transition metal catalysis.
• Process Chemistry & Scale-up: Employed in the optimization and commercial-scale manufacturing of enantiomerically pure compounds.
• Agrochemical Research: Utilized in the synthesis of chiral active ingredients for advanced crop protection agents.
• Material Science: A building block for creating chiral polymers and organic electronic materials with specific optical properties.

Basic Information

Product Name	(R)-Boroabu-(+)-Pinanediol-Hcl
CAS No.	319009-92-2
Molecular Formula	C16H28BClNO2
Molecular Weight	311.66 g/mol
Synonyms	(R)-2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-N,N,N-trimethylethanaminium Chloride; (R)-Boroabu Pinanediol Ester Hydrochloride; (R)-2-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)-1,2,2-trimethylcyclopentan-1-amine Hydrochloride; (R)-Pinanediol Boronate Ester HCl Salt; (R)-Boro-tert-butylalanine Pinanediol Ester Hydrochloride; (R)-BoroAbu(Pin) HCl; Chiral Aminoalkylboronic Acid Pinanediol Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Boroabu-(+)-Pinanediol-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR (1H, 11B, 13C), and mass spectrometry, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.