Description

2-Fluoro-4-(Trifluoromethyl)Thiobenzamide is a high-purity fluorinated thiobenzamide derivative, a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both fluorine and a trifluoromethyl group, making it an essential intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This product is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and fluorinated components.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethyl)Thiobenzamide
CAS No.	317319-34-9
Molecular Formula	C8H5F4NS
Molecular Weight	223.19 g/mol
Synonyms	2-Fluoro-4-(trifluoromethyl)benzenecarbothioamide; 4-(Trifluoromethyl)-2-fluorothiobenzamide; 2-Fluoro-alpha,alpha,α-trifluoro-p-thiobenzamide; Thiobenzamide, 2-fluoro-4-(trifluoromethyl)-; 2-Fluoro-4-trifluoromethylthiobenzamide; 2-Fluoro-4-(trifluoromethyl)benzothioamide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Trifluoromethyl)Thiobenzamide is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.