Description

2H-Pyran-3-Ol,5-Fluorotetrahydro-2-Methoxy-6-Methyl-,(2S,3R,5S,6R)-(9Ci) is a high-purity, stereochemically defined fluorinated pyran derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate for the synthesis of complex bioactive molecules. It is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for projects requiring precise stereochemistry and fluorine incorporation to modulate the properties of target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in antiviral, antibacterial, and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced fluorinated candidates for new-generation herbicides, fungicides, and pesticides, leveraging fluorine's ability to enhance bioavailability and metabolic stability.
• Organic Synthesis Building Block: Provides a versatile scaffold for medicinal and process chemists to construct complex molecular architectures with defined stereocenters.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on the reactivity and physical properties of heterocyclic systems.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the optimization and commercial-scale production routes for fluorinated target molecules.

Basic Information

Product Name	2H-Pyran-3-Ol,5-Fluorotetrahydro-2-Methoxy-6-Methyl-,(2S,3R,5S,6R)-(9Ci)
CAS No.	316129-07-4
Molecular Formula	C7H13FO3
Molecular Weight	164.18 g/mol
Synonyms	(2S,3R,5S,6R)-5-Fluoro-2-methoxy-6-methyltetrahydro-2H-pyran-3-ol; 5-Fluoro-2-methoxy-6-methyltetrahydro-2H-pyran-3-ol (stereoisomer); Tetrahydro-2H-pyran-3-ol, 5-fluoro-2-methoxy-6-methyl-, (2S,3R,5S,6R)-; Fluorinated tetrahydropyranol; Chiral fluoropyran derivative; Advanced fluorinated synthon. Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our 2H-Pyran-3-Ol,5-Fluorotetrahydro-2-Methoxy-6-Methyl-,(2S,3R,5S,6R)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including chiral HPLC, GC, NMR, and MS to verify identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.