Description

2-Chloro-1-[1-(3-Chloro-4-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]Ethanone is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. Pharmaceutical manufacturers and R&D laboratories need this material for developing new therapeutic agents and scaling up production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct complex molecular architectures for final APIs.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in pilot plant and commercial manufacturing for process development and validation.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of proprietary compounds under cGMP conditions.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-Chloro-1-[1-(3-Chloro-4-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]Ethanone
CAS No.	315710-83-9
Molecular Formula	C14H12Cl2FNO
Molecular Weight	300.16 g/mol
Synonyms	2-Chloro-1-[1-(3-chloro-4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]ethanone; 1-(3-Chloro-4-fluorophenyl)-2,5-dimethyl-3-(2-chloroacetyl)-1H-pyrrole; 3-(2-Chloroacetyl)-1-(3-chloro-4-fluorophenyl)-2,5-dimethyl-1H-pyrrole; 2-Chloro-1-(1-(3-chloro-4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)ethan-1-one; Ethanone, 2-chloro-1-[1-(3-chloro-4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-; CAS 315710-83-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-[1-(3-Chloro-4-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrol-3-Yl]Ethanone is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can support development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.