Description

4-({[(4-Fluorophenyl)Amino]Carbonothioyl}Amino)-n-1,3-Thiazol-2-Ylbenzenesulfonamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. Its unique molecular architecture, featuring a sulfonamide core linked to a fluorophenyl-thiazole moiety, makes it a critical building block for targeted drug discovery. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on developing enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting specific enzymes or biological pathways.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic assays and receptor binding studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.

Basic Information

Product Name	4-({[(4-Fluorophenyl)Amino]Carbonothioyl}Amino)-n-1,3-Thiazol-2-Ylbenzenesulfonamide
CAS No.	314764-52-8
Molecular Formula	C16H12FN5O2S2
Molecular Weight	397.42 g/mol
Synonyms	4-({[(4-Fluorophenyl)Amino]Carbonothioyl}Amino)-N-(1,3-Thiazol-2-yl)benzenesulfonamide; 4-[(4-Fluorophenyl)thioureido]-N-(thiazol-2-yl)benzenesulfonamide; N-(4-Fluorophenyl)-N'-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]thiourea; 4-[(4-Fluorophenyl)carbamothioylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide; CAS 314764-52-8; 4-({[(4-Fluorophenyl)Amino]Carbonothioyl}Amino)-n-1,3-thiazol-2-ylbenzenesulfonamide
EINECS	Contact for details

Quality Control

Our 4-({[(4-Fluorophenyl)Amino]Carbonothioyl}Amino)-n-1,3-Thiazol-2-Ylbenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.