Description

1-[(4-Fluorophenyl)Sulfonyl]Indoline is a high-purity sulfonamide derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated sulfonyl pharmacophores into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of biologically active molecules, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorophenylsulfonyl moiety can enhance bioavailability and target specificity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced materials with tailored properties.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target compounds under cGMP conditions.

Basic Information

Product Name	1-[(4-Fluorophenyl)Sulfonyl]Indoline
CAS No.	314054-14-3
Molecular Formula	C14H12FNO2S
Molecular Weight	277.31 g/mol
Synonyms	1-(4-Fluorobenzenesulfonyl)indoline; N-(4-Fluorophenylsulfonyl)indoline; Indoline, 1-[(4-fluorophenyl)sulfonyl]-; 4-Fluoro-N-(2,3-dihydro-1H-indol-1-yl)benzenesulfonamide; 1-(4-Fluorophenylsulfonyl)-2,3-dihydro-1H-indole; 4-Fluorobenzenesulfonamide, N-2,3-dihydro-1H-indol-1-yl-; 1H-Indole, 2,3-dihydro-1-[(4-fluorophenyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our 1-[(4-Fluorophenyl)Sulfonyl]Indoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.