Description

3 3 3-Trifluoro-1-Phenyl-1 2-Propanediol is a high-value fluorinated organic building block characterized by a phenyl ring and a trifluoromethyl-substituted diol moiety. This compound is essential for introducing the trifluoromethyl group, which can dramatically alter the physicochemical properties of target molecules, enhancing their metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active pharmaceutical ingredients (APIs), and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in creating novel herbicides and pesticides where the CF3 group improves weatherfastness and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals with unique optical and electronic properties.
• Fluorine Chemistry Research: A valuable standard and starting material in academic and industrial laboratories exploring new fluorination methodologies.

Basic Information

Product Name	3 3 3-Trifluoro-1-Phenyl-1 2-Propanediol
CAS No.	314041-39-9
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	1-Phenyl-3,3,3-trifluoropropane-1,2-diol; 3,3,3-Trifluoro-1-phenyl-1,2-propanediol; α-(Trifluoromethyl)mandelic alcohol; (RS)-3,3,3-Trifluoro-1-phenyl-1,2-propanediol; 3,3,3-Trifluoro-2-hydroxy-1-phenyl-1-propanol; (±)-3,3,3-Trifluoro-1-phenyl-1,2-propanediol; Trifluoromethylphenyl glycol
EINECS	Contact for details

Quality Control

Our 3 3 3-Trifluoro-1-Phenyl-1 2-Propanediol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Consider storing under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.