Description

5,6,7-Trifluoro-3,4-Dihydro-1H-Naphthalen-2-One is a high-value, fluorinated organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a fused ring system with strategic fluorine substitution, makes it a critical intermediate for developing novel compounds with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Acts as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic core.
• Fluorine Chemistry Studies: Employed in academic and industrial laboratories to study structure-activity relationships (SAR) and the effects of polyfluorination on molecular properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, fluorinated naphthalene derivatives.

Basic Information

Product Name	5,6,7-Trifluoro-3,4-Dihydro-1H-Naphthalen-2-One
CAS No.	313947-31-8
Molecular Formula	C₁₀H₅F₃O
Molecular Weight	204.14 g/mol
Synonyms	5,6,7-Trifluoro-3,4-dihydro-2(1H)-naphthalenone; 5,6,7-Trifluoro-1,2,3,4-tetrahydronaphthalen-2-one; 5,6,7-Trifluoro-3,4-dihydronaphthalen-2(1H)-one; 2-Oxo-5,6,7-trifluoro-1,2,3,4-tetrahydronaphthalene; 5,6,7-Trifluoro-α-tetralone; 313947-31-8; 5,6,7-Trifluoro-2-tetralone
EINECS	Contact for details

Quality Control

Our 5,6,7-Trifluoro-3,4-Dihydro-1H-Naphthalen-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.