Description

2-Butanone, 3,4,4-Trifluoro- (9Ci) is a fluorinated ketone building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl group, enabling the introduction of fluorine atoms to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the fluorine atoms improve weather resistance and biological activity.
• Material Science Research: Serves as a precursor for fluorinated polymers and specialty chemicals with unique surface properties and chemical resistance.
• Liquid Crystal & Electronic Chemicals: A potential building block for fluorinated components in display materials and dielectric fluids.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a substrate for developing new fluorination methodologies in academic and industrial R&D.

Basic Information

Product Name	2-Butanone, 3,4,4-Trifluoro- (9Ci)
CAS No.	313271-61-3
Molecular Formula	C4H5F3O
Molecular Weight	126.08 g/mol
Synonyms	3,4,4-Trifluorobutan-2-one; 1,1,1-Trifluoro-3-butanone; 3,4,4-Trifluoro-2-butanone; 3,4,4-Trifluorobutanone; 3,4,4-Trifluoro-2-oxobutane; 3,4,4-Trifluoro-2-butanone (9CI); 3,4,4-Trifluoro-2-butanone (9CI) (CAS 313271-61-3)
EINECS	Contact for details

Quality Control

Every batch of 2-Butanone, 3,4,4-Trifluoro- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.