Description

(2-Trifluoromethyl-Benzoimidazol-1-Yl)-Acetic Acid is a high-purity, functionalized benzimidazole derivative of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate, enabling the introduction of the trifluoromethyl-benzimidazole pharmacophore into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where its unique structure can impart desirable biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzimidazole core.
• Material Science Research: Serves as a precursor for specialty chemicals, ligands, or monomers in the development of advanced polymers and functional materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Product Name	(2-Trifluoromethyl-Benzoimidazol-1-Yl)-Acetic Acid
CAS No.	313241-14-4
Molecular Formula	C10H7F3N2O2
Molecular Weight	244.17 g/mol
Synonyms	2-(2-Trifluoromethyl-1H-benzimidazol-1-yl)acetic acid; 1H-Benzimidazole-1-acetic acid, 2-(trifluoromethyl)-; (2-Trifluoromethyl-1H-benzimidazol-1-yl)acetic acid; α-((2-Trifluoromethyl)benzimidazol-1-yl)acetic acid; 2-(2-Trifluoromethylbenzimidazol-1-yl)acetic acid; (2-Trifluoromethyl-1-benzimidazolyl)acetic acid; 313241-14-4; CF3-BIA
EINECS	Contact for details

Quality Control

Our (2-Trifluoromethyl-Benzoimidazol-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.