Description

(2E)-1-(4-Fluorophenyl)-3-(4-Methylphenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct molecular structure. This compound is a critical advanced intermediate for the research and development of novel active pharmaceutical ingredients (APIs) and functional organic materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in the development of anti-inflammatory, anticancer, and antimicrobial agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and hit-to-lead optimization in drug discovery programs.
• Agrochemical Synthesis: Acts as a precursor for developing new crop protection agents and pesticides with enhanced efficacy.
• Organic Electronic Materials: Investigated as a potential component in the development of organic light-emitting diodes (OLEDs) and photovoltaic materials due to its conjugated system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Flavor & Fragrance Industry: May be used as an intermediate for synthesizing complex aroma chemicals.

Basic Information

Product Name	(2E)-1-(4-Fluorophenyl)-3-(4-Methylphenyl)Prop-2-En-1-One
CAS No.	313236-80-5
Molecular Formula	C16H13FO
Molecular Weight	240.27 g/mol
Synonyms	4'-Fluoro-4-Methylchalcone; (E)-1-(4-Fluorophenyl)-3-(p-tolyl)prop-2-en-1-one; 3-(4-Methylphenyl)-1-(4-fluorophenyl)-2-propen-1-one; p-Fluorophenyl p-Tolyl Ketone, Chalcone Derivative; 4-Fluoro-4'-methylchalcone; (E)-3-(4-Methylphenyl)-1-(4-fluorophenyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our (2E)-1-(4-Fluorophenyl)-3-(4-Methylphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.