Description

3-(4-Methylphenyl)-5-{[1-Phenyl-3-(2-Thienyl)-1H-Pyrazol-4-Yl]Methylene}-2-Thioxo-1,3-Thiazolidin-4-One is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its unique molecular architecture, featuring fused pyrazole and thiazolidinone rings, makes it a valuable building block for developing novel functional materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its heterocyclic core.
• Material Science: Building block for creating specialized polymers, dyes, or organic electronic materials due to its conjugated system.
• Chemical Biology: Serves as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Essential for exploratory synthesis in university and corporate research laboratories focusing on heterocyclic chemistry.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	3-(4-Methylphenyl)-5-{[1-Phenyl-3-(2-Thienyl)-1H-Pyrazol-4-Yl]Methylene}-2-Thioxo-1,3-Thiazolidin-4-One
CAS No.	312745-95-2
Molecular Formula	C24H17N3OS2
Molecular Weight	427.54 g/mol
Synonyms	5-[(1-Phenyl-3-thiophen-2-yl-1H-pyrazol-4-yl)methylidene]-3-(4-methylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one; 3-(p-Tolyl)-5-{[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]methylene}-2-thioxothiazolidin-4-one; CAS 312745-95-2; Thiazolidinone derivative, Pyrazolylmethylene thiazolidinone; Advanced heterocyclic intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Methylphenyl)-5-{[1-Phenyl-3-(2-Thienyl)-1H-Pyrazol-4-Yl]Methylene}-2-Thioxo-1,3-Thiazolidin-4-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.