Description

(E)-1-Hexene-1,2-Diboronic Acid Bis(Pinacol) Ester is a high-purity, advanced organic boron reagent featuring a defined stereochemistry and two reactive boronic ester groups. This compound is a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation and the construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling and iterative synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific alkene-boronate functionality.
• Materials Science & OLED Development: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile coupling partner with aryl or vinyl halides to form new C-C bonds with high stereochemical fidelity.
• Chemical Biology & Probe Development: Utilized for the site-specific labeling and modification of biomolecules.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(E)-1-Hexene-1,2-Diboronic Acid Bis(Pinacol) Ester
CAS No.	312693-52-0
Molecular Formula	C18H34B2O4
Molecular Weight	336.08 g/mol
Synonyms	(E)-1-Hexene-1,2-diyldiboronic Acid Bis(Pinacol) Ester; (E)-1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)hex-1-ene; 1-Hexene-1,2-diboronic Acid Pinacol Ester (E-isomer); trans-1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-hexene; 312693-52-0; Hex-1-ene-1,2-diyldiboronic Acid Bis(2,3-dimethylbutane-2,3-diol) Ester
EINECS	Contact for details

Quality Control

Our (E)-1-Hexene-1,2-Diboronic Acid Bis(Pinacol) Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to confirm identity, assay, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain product integrity and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (GC/HPLC)	≥ 95.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.