Description

4-Biphenylzinc Bromide is a versatile organozinc reagent, specifically a biphenyl-functionalized organometallic compound, widely used in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it serves as a critical building block for active pharmaceutical ingredients (APIs), liquid crystal materials, and organic electronic components.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Negishi and other cross-coupling reactions for the synthesis of biphenyl-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used to construct complex aromatic structures found in advanced herbicides, fungicides, and plant growth regulators.
• Materials Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials for OLEDs and electronic devices.
• Catalyst & Ligand Preparation: Serves as a precursor for the synthesis of specialized ligands and organometallic catalysts.
• Fine Chemical Manufacturing: Facilitates the production of specialty aromatic compounds used in flavors, fragrances, and dyes.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and organometallic chemistry.

Basic Information

Product Name	4-Biphenylzinc Bromide
CAS No.	312693-44-0
Molecular Formula	C12H9BrZn
Molecular Weight	290.48 g/mol
Synonyms	p-Phenylphenylzinc bromide; (1,1'-Biphenyl)-4-ylzinc bromide; 4-Biphenylylzinc bromide; (4-Biphenylyl)zinc bromide; Tetrahydrofuran complex of (1,1'-Biphenyl-4-yl)zinc bromide; Zinc, (1,1'-biphenyl-4-yl)bromo-; Biphenyl-4-ylzinc bromide
EINECS	Contact for details

Quality Control

Our production of 4-Biphenylzinc Bromide CAS NO 312693-44-0 adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is rigorously analyzed to confirm identity, purity, and concentration, typically supplied as a solution in tetrahydrofuran (THF). A comprehensive Certificate of Analysis (COA) detailing assay (by titration), residual moisture (Karl Fischer), and other critical parameters is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized (store under inert atmosphere). For optimal stability, store the sealed container under an inert gas (argon or nitrogen) at 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (as C12H9BrZn)	0.5 M in THF (Typical)
Purity (Titration)	≥ 95%
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.