Description

3-Methylphenylzinc Iodide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its value lies in enabling highly selective carbon-carbon bond formation, particularly in Negishi cross-coupling reactions, which are critical for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and efficient synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific aryl-methyl substitutions.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystals.
• Negishi Cross-Coupling Reactions: The primary application, facilitating the coupling of aryl groups with various electrophiles in the presence of palladium catalysts.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, flavors, and fragrances where high regioselectivity is required.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploring new synthetic routes in organometallic chemistry.

Basic Information

Item	Detail
Product Name	3-Methylphenylzinc Iodide
CAS No.	312693-24-6
Molecular Formula	C7H7IZn
Molecular Weight	283.43 g/mol
Synonyms	(3-Methylphenyl)zinc iodide; m-Tolylzinc iodide; 3-Methylbenzenezinc iodide; Zinc, (3-methylphenyl)-, iodide (1:1); m-Tolylzinc iodide solution
EINECS	Contact for details

Quality Control

Our 3-Methylphenylzinc Iodide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and solution concentration. Certificates of Analysis (COA) detailing specific assay results (typically by titration) and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and highly volatile. Keep away from heat, sparks, and open flame. Use only in a well-ventilated fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zn basis)	≥ 95%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.