Description

2-Methylphenylzinc Iodide is an organozinc reagent, specifically an arylzinc halide, widely used in modern synthetic organic chemistry. This compound matters for its role as a key coupling partner in cross-coupling reactions, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• As a nucleophilic coupling agent in Negishi cross-coupling reactions with aryl/vinyl halides or triflates.
• For the synthesis of biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• In the preparation of liquid crystal and organic light-emitting diode (OLED) materials requiring specific aryl-aryl linkages.
• As a transmetalation agent in catalytic cycles for constructing C-C bonds under mild conditions.
• For functionalizing complex molecules in late-stage diversification within medicinal chemistry programs.
• In academic and industrial research for developing new catalytic methodologies.

Basic Information

Product Name	2-Methylphenylzinc Iodide
CAS No.	312693-23-5
Molecular Formula	C7H7IZn
Molecular Weight	283.43 g/mol
Synonyms	(2-Methylphenyl)zinc iodide; o-Tolylzinc iodide; 2-Tolylzinc iodide; Zinc, (2-methylphenyl)iodo-; (o-Tolyl)zinc iodide; Iodo(2-methylphenyl)zinc; (2-Methylphenyl)iodozinc
EINECS	Contact for details

Quality Control

Our 2-Methylphenylzinc Iodide is produced under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. The product undergoes rigorous analysis, including titration for active zinc content and spectroscopic methods to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and solution concentration is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. Due to its moisture-sensitive and easily oxidized nature, the reagent should be handled under inert conditions using standard Schlenk or glovebox techniques to maintain purity and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (Typical)	0.5 M in Tetrahydrofuran (THF)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.