Description

5-Cyano-5-Methylhexylzinc Bromide is a highly reactive organozinc reagent, specifically a functionalized alkylzinc bromide, widely utilized in modern synthetic organic chemistry. Its value lies in its ability to serve as a versatile nucleophile for carbon-carbon bond formation, particularly in cross-coupling reactions, enabling the efficient synthesis of complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and reliable building blocks for constructing novel chemical entities.

Application

• As a key nucleophilic coupling partner in Negishi, Kumada, and related transition-metal catalyzed cross-coupling reactions.
• For the introduction of the 5-cyano-5-methylhexyl moiety into complex organic frameworks, such as active pharmaceutical ingredients (APIs) and agrochemical intermediates.
• In the synthesis of specialty polymers and functional materials where its unique branched alkyl chain with a terminal nitrile group imparts specific physical properties.
• As a precursor for further functional group transformations, where the nitrile group can be hydrolyzed to carboxylic acids or reduced to amines.
• For academic and industrial R&D in methodology development and the exploration of new synthetic pathways.

Basic Information

Product Name	5-Cyano-5-Methylhexylzinc Bromide
CAS No.	312693-22-4
Molecular Formula	C8H14BrNZn
Molecular Weight	261.50 g/mol
Synonyms	5-Methyl-5-cyanohexylzinc bromide; (5-Cyano-5-methylhexyl)zinc bromide; Zinc, bromo(5-cyano-5-methylhexyl)-; 5-Cyano-5-methyl-1-zincabromo-hexane
EINECS	Contact for details

Quality Control

Our 5-Cyano-5-Methylhexylzinc Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including titration for active zinc content and spectroscopic identification. A Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or other solvents), and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions, or as specified on the label. Due to its moisture-sensitive and easily oxidized nature, the reagent must be handled using standard Schlenk or glovebox techniques to prevent decomposition and maintain efficacy.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.