Description

3-Methylbenzylzinc Chloride is a versatile organozinc reagent, specifically a benzylzinc halide, widely used in modern organic synthesis. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, making it a critical building block for advanced chemical intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity reagents for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Negishi and other cross-coupling reactions for the introduction of the 3-methylbenzyl moiety into active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific benzyl-substituted structures.
• Ligand & Catalyst Development: Serves as a precursor in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers with tailored properties.
• Fine Chemical Production: Facilitates the synthesis of complex fragrance and flavor compounds where precise structural control is paramount.
• Academic & Industrial R&D: A fundamental tool for methodological development in organometallic chemistry and new synthetic pathway exploration.

Basic Information

Item	Detail
Product Name	3-Methylbenzylzinc Chloride
CAS No.	312693-20-2
Molecular Formula	C8H9ClZn
Molecular Weight	205.99 g/mol
Synonyms	(3-Methylbenzyl)zinc Chloride; Zinc, chloromethyl-3-methylphenyl-; 1-(Chlorozinciomethyl)-3-methylbenzene; m-Tolylmethylzinc Chloride; 3-Methylbenzyl Chlorozinc; (m-Tolylmethyl)zinc Chloride; Organozinc Reagent 312693-20-2
EINECS	Contact for details

Quality Control

Our 3-Methylbenzylzinc Chloride is manufactured under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including titration for active zinc content and spectroscopic methods (NMR, IR) for structural confirmation and purity assessment. We provide Certificates of Analysis (COA) with every shipment, detailing batch-specific results to ensure traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly moisture-sensitive and pyrophoric nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For extended stability, storage at temperatures between 2°C and 8°C is recommended. Keep away from heat, sparks, open flames, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF or ether)
Concentration	0.5 M in THF, 1.0 M in Diethyl Ether (or as specified)
Assay (Titration)	≥ 95% (as Zn)
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98% (by GC area)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.