Description

(S)-(-)-3-Methoxy-2-Methyl-3-Oxopropylzinc Bromide is a high-purity, chiral organozinc reagent essential for advanced synthetic chemistry. This compound matters because it enables the stereoselective formation of carbon-carbon bonds, a critical step in constructing complex molecular architectures. Pharmaceutical, agrochemical, and fine chemical R&D laboratories need it for the efficient synthesis of enantiomerically pure intermediates and active ingredients. Its application is pivotal in developing novel therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the stereoselective synthesis of chiral active pharmaceutical ingredients (APIs) and complex drug candidates.
• Asymmetric Catalysis & Ligand Development: Used in the preparation of chiral ligands and catalysts for enantioselective transformations.
• Agrochemical Manufacturing: Employed in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Facilitates the creation of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and process chemistry research.
• Material Science Precursor: Potential use in synthesizing chiral polymers or advanced organic materials with specific optical properties.

Basic Information

Product Name	(S)-(-)-3-Methoxy-2-Methyl-3-Oxopropylzinc Bromide
CAS No.	312693-18-8
Molecular Formula	C6H11BrO2Zn
Molecular Weight	236.45 g/mol
Synonyms	(S)-(-)-3-Methoxy-2-methyl-3-oxopropylzinc bromide; (S)-Methyl 2-methyl-3-(bromozincio)propanoate; (S)-Methyl 2-methyl-3-(bromozincio)propionate; (S)-Methyl 3-bromozincio-2-methylpropanoate; (S)-3-Methoxy-2-methyl-3-oxo-1-propylzinc bromide; Zinc, bromo[(1S)-2-methoxy-1-methyl-2-oxoethyl]-; (S)-(-)-Methyl 3-bromozincio-2-methylpropionate
EINECS	Contact for details

Quality Control

Our (S)-(-)-3-Methoxy-2-Methyl-3-Oxopropylzinc Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed to confirm identity, assay, enantiomeric excess, and impurity profile. Certificates of Analysis (COA) documenting these results are available upon request. Our quality management system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. This compound is hygroscopic (moisture-sensitive) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. The container must be kept tightly sealed to exclude moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 0.5 M in specified solvent (e.g., THF)
Enantiomeric Excess (HPLC/Chiral GC)	≥ 98.0% ee
Zinc Content	Conforms
Bromide Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.