Description

2-Methoxybenzylzinc Chloride is an organozinc reagent, specifically an arylzinc halide, widely used in organic synthesis. Its primary value lies in enabling efficient carbon-carbon bond formation through cross-coupling reactions, offering excellent functional group tolerance and selectivity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity building blocks for complex molecule construction.

Application

• Key intermediate in pharmaceutical synthesis for constructing complex drug molecules and active pharmaceutical ingredients (APIs).
• Critical reagent in Negishi cross-coupling reactions for the selective formation of biaryl and alkyl-aryl bonds.
• Used in the development of agrochemicals, including herbicides, fungicides, and insecticides.
• Building block for liquid crystal materials and other advanced organic electronic components.
• Employed in academic and industrial R&D for methodological studies in organometallic chemistry.
• Precursor for the synthesis of fine chemicals and specialty fragrances.

Basic Information

Product Name	2-Methoxybenzylzinc Chloride
CAS No.	312693-15-5
Molecular Formula	C8H9ClOZn
Molecular Weight	221.99 g/mol
Synonyms	(2-Methoxybenzyl)zinc chloride; o-Methoxybenzylzinc chloride; Zinc, chloro(2-methoxyphenyl)methyl-; (2-Methoxyphenyl)methylzinc chloride; 2-Methoxybenzylzinc chloride solution; o-Methoxybenzyl zinc chloride; (o-Methoxybenzyl)zinc chloride; Benzene, 1-(chlorozinciomethyl)-2-methoxy-
EINECS	Contact for details

Quality Control

Our 2-Methoxybenzylzinc Chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes comprehensive analysis, including titration for active zinc content and spectroscopic identification. Certificates of Analysis (COA) detailing purity, concentration (if supplied in solution), and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), this material must be handled and stored under an inert gas atmosphere (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF or ether)
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zinc content)	≥ 95%
Water Content (KF)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.