Description

4-Ethylphenylzinc Iodide is a versatile organozinc reagent, specifically an arylzinc halide, widely used in modern organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 4-ethylphenyl moiety into target molecules via Negishi, Kumada, or other transition-metal-catalyzed cross-coupling reactions.
• Agrochemical Active Ingredient Development: Used in the research and production of herbicides, fungicides, and insecticides that incorporate substituted phenyl groups.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise aryl group functionalization is critical.
• Fine Chemical and Specialty Chemical Production: Facilitates the manufacture of dyes, pigments, and other performance chemicals requiring specific aryl substitutions.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	4-Ethylphenylzinc Iodide
CAS No.	312693-04-2
Molecular Formula	C8H9IZn
Molecular Weight	297.45 g/mol
Synonyms	(4-Ethylphenyl)zinc iodide; Zinc, (4-ethylphenyl)iodo-; p-Ethylphenylzinc iodide; 1-Ethyl-4-(iodozincio)benzene; 4-Ethylbenzenezinc iodide; (p-Ethylphenyl)zinc iodide; Arylzinc halide reagent
EINECS	Contact for details

Quality Control

Our production of 4-Ethylphenylzinc Iodide adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is rigorously analyzed to confirm identity, purity, and solution concentration (typically supplied in THF or ether). Certificates of Analysis (COA) detailing assay results (often by titration or NMR), residual moisture, and other critical parameters are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. This material is moisture-sensitive (hygroscopic) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep the container sealed in a cool, dry, well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR/IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zn basis)	≥ 95%
Water Content (Karl Fischer)	≤ 100 ppm
Solvent	Anhydrous Tetrahydrofuran (THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.