Description

6-Ethoxy-6-Oxohexylzinc Bromide is a highly reactive organozinc reagent, specifically an alkylzinc bromide, widely utilized in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation through cross-coupling reactions, offering superior functional group tolerance and selectivity compared to traditional organometallic reagents. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable methods for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the introduction of functionalized hexyl chains into active pharmaceutical ingredients (APIs) via Negishi and related cross-coupling reactions.
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific alkyl modifications for enhanced efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Employed in the creation of novel polymers and organic electronic materials where precise alkyl chain length and terminal functionality are critical.
• Fine Chemical Manufacturing: Facilitates the production of specialty flavors, fragrances, and dyes through controlled alkylation steps.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and exploring new reaction pathways.

Basic Information

Product Name	6-Ethoxy-6-Oxohexylzinc Bromide
CAS No.	312693-01-9
Molecular Formula	C8H15BrO2Zn
Molecular Weight	288.50 g/mol
Synonyms	6-Ethoxy-6-oxohexylzinc bromide; Ethyl 6-(bromozincio)hexanoate; Hexanoic acid, 6-(bromozincio)-, ethyl ester; Bromo(6-ethoxy-6-oxohexyl)zinc; Organozinc reagent 312693-01-9; Ethyl 6-bromozinciohexanoate; (6-Ethoxy-6-oxohexyl)zinc bromide
EINECS	Contact for details

Quality Control

Every batch of 6-Ethoxy-6-Oxohexylzinc Bromide is manufactured and tested under stringent quality management systems to ensure consistency and reliability for critical synthetic applications. Our products undergo rigorous quality testing, including titration for active zinc content and spectroscopic analysis for identity and purity verification, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for extended stability. The container should be kept tightly sealed and allowed to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Concentration (Titration)	0.5 M in THF (or as specified)
Assay (Active Zn)	≥ 95%
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.