Description

3,4-Dimethylphenylzinc Iodide is a highly reactive organozinc reagent used as a key building block in advanced organic synthesis. This compound matters for its ability to facilitate efficient carbon-carbon bond formation, specifically in Negishi cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional compounds. Its utility lies in introducing the 3,4-dimethylphenyl moiety into target molecules with high selectivity.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing active pharmaceutical ingredients (APIs), especially those containing substituted biphenyl or terphenyl structures.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl group incorporation.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and advanced polymers where the 3,4-dimethylphenyl group modifies electronic or physical properties.
• Negishi Cross-Coupling Reactions: Serves as a superior organometallic coupling partner with various organic halides (e.g., aryl, vinyl, alkynyl halides) catalyzed by palladium or nickel.
• Fine Chemical and Ligand Preparation: Key for synthesizing specialized ligands for catalysis and other high-value, low-volume fine chemicals.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new synthetic pathways in research laboratories.

Basic Information

Product Name	3,4-Dimethylphenylzinc Iodide
CAS No.	312692-97-0
Molecular Formula	C8H9IZn
Molecular Weight	297.45 g/mol
Synonyms	(3,4-Dimethylphenyl)zinc iodide; Zinc, (3,4-dimethylphenyl)iodo-; 3,4-Dimethylbenzenezinc iodide; 1-Iodozinc-3,4-dimethylbenzene; 3,4-Xylylzinc iodide; (3,4-DMP)ZnI
EINECS	Contact for details

Quality Control

Every batch of our 3,4-Dimethylphenylzinc Iodide is manufactured and handled under strict inert atmosphere conditions to ensure purity and reactivity. We employ advanced analytical techniques, including titration (for zinc and active species content) and GC/HPLC analysis, to verify chemical identity and quantify major impurities. Certificates of Analysis (COA) detailing batch-specific results are provided and we support compliance with relevant REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C. The container should be kept in a cool, dry, well-ventilated place, away from incompatible materials such as strong acids, oxidizers, and water.

Specification

Item	Specification
Appearance	Solution (typically in THF or Ether), Colorless to light yellow
Identification (NMR/IR)	Conforms to structure
Assay (Titration)	0.5 M in solvent (or as specified)
Purity (GC/HPLC)	≥ 95% (organozinc species)
Zinc Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.