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3,5-Dichlorophenylzinc Iodide CAS NO 312692-86-7
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CAS No.:312692-86-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3,5-Dichlorophenylzinc Iodide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, specifically in Negishi cross-coupling reactions, which are critical for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for the synthesis of novel compounds.
Application
- Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
- Agrochemical Development: Used in the synthesis of advanced herbicides, fungicides, and insecticides containing dichlorophenyl motifs.
- Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystals.
- Negishi Cross-Coupling Reactions: The primary application, facilitating the coupling with various organic electrophiles like aryl halides or triflates.
- Catalyst & Ligand Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
- Custom Chemical Synthesis: Provides a reliable route for contract research organizations (CROs) and fine chemical producers to access bespoke, complex organic structures.
Basic Information
| Item | Details |
|---|---|
| Product Name | 3,5-Dichlorophenylzinc Iodide |
| CAS No. | 312692-86-7 |
| Molecular Formula | C6H3Cl2IZn |
| Molecular Weight | 328.26 g/mol |
| Synonyms | (3,5-Dichlorophenyl)zinc iodide; Zinc, (3,5-dichlorophenyl)iodo-; 3,5-Dichlorophenylzinc iodide solution; (3,5-Dichlorophenyl)iodozinc; Iodo(3,5-dichlorophenyl)zinc; Organozinc reagent 3,5-Cl2PhZnI |
| EINECS | Contact for details |
Quality Control
Every batch of 3,5-Dichlorophenylzinc Iodide is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure product integrity and batch-to-batch consistency, which is critical for reproducible cross-coupling reactions. A Certificate of Analysis (COA) detailing assay (typically by titration or ICP), solvent content, and impurity profile is supplied with each shipment. Our quality systems support compliance with cGMP and ISO standards for advanced chemical intermediates.
Storage
Preserve in a tightly closed container, protected from light. This material is moisture-sensitive (hygroscopic) and should be stored under an inert atmosphere (argon or nitrogen) to prevent oxidation and hydrolysis. For optimal stability, store at 2-8°C in a cool, dry, well-ventilated area. Keep away from strong acids and incompatible solvents.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow solution |
| Identification (NMR/IR) | Conforms to structure |
| Assay (Titration) | 0.5 M in THF (or as specified) |
| Zinc Content | Contact for details |
| Solvent (THF) | Balance |
| Water Content (KF) | < 100 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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