Description

5-Chloro-2-Thienylzinc Bromide is a versatile organozinc reagent, a key building block for the formation of carbon-carbon bonds in complex organic synthesis. Its value lies in its high reactivity and selectivity in cross-coupling reactions, enabling the efficient construction of functionalized heterocyclic compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those containing functionalized thiophene scaffolds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific chlorothienyl motifs.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials for OLEDs and semiconductors.
• Cross-Coupling Reactions: Employed in Negishi, Kumada, and other transition-metal-catalyzed couplings to introduce the 5-chloro-2-thienyl group into target molecules.
• Ligand and Catalyst Development: Used to synthesize novel organometallic complexes and ligands for catalytic applications.
• Fine Chemical Production: Enables the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	5-Chloro-2-Thienylzinc Bromide
CAS No.	312624-22-9
Molecular Formula	C4H2BrClSZn
Molecular Weight	260.88 g/mol
Synonyms	5-Chloro-2-thienylzinc bromide; 5-Chloro-2-thienylzinc bromide solution; 2-Bromo-5-chlorothiophene zinc derivative; Zinc, (5-chloro-2-thienyl)bromo-; (5-Chlorothiophen-2-yl)zinc bromide; 5-Chlorothiophene-2-zinc bromide; Bromo(5-chloro-2-thienyl)zinc
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Thienylzinc Bromide is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as concentration, assay, and impurity profile. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting your regulatory and compliance needs in target industries.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For long-term stability, maintain at recommended temperatures between 2°C and 8°C. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Solution (typically in THF)
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Purity (HPLC)	≥ 98% (by area)
Water Content (KF)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.