Description

5-Chloropentylzinc Bromide is a versatile organozinc reagent, specifically a functionalized alkylzinc halide, widely used in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation through cross-coupling reactions, such as Negishi coupling, which is critical for constructing complex molecular architectures. This compound is particularly essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 5-chloropentyl moiety into target molecules during the research and development of new drug candidates.
• Negishi Cross-Coupling Reactions: Serves as a robust nucleophilic partner with various aryl, heteroaryl, and vinyl halides or triflates to form new C-C bonds under mild conditions.
• Agrochemical Active Ingredient Production: Used in the synthesis of herbicides, fungicides, and insecticides that require specific chlorinated alkyl chains.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Utilized in the synthesis of functional polymers and organic electronic materials where precise chain length and terminal functionality are required.
• Fine Chemical and Flavor/Fragrance Synthesis: Applied in the multi-step synthesis of complex natural products and specialty aroma chemicals.

Basic Information

Item	Details
Product Name	5-Chloropentylzinc Bromide
CAS No.	312624-21-8
Molecular Formula	C5H10BrClZn
Molecular Weight	250.89 g/mol
Synonyms	Bromo(5-chloropentyl)zinc; (5-Chloropentyl)zinc bromide; Zinc, bromo(5-chloropentyl)-; 5-Chloroamylzinc bromide; 1-Chloro-5-(bromozincio)pentane; (5-Chloro-1-pentyl)zinc bromide; Bromo(5-chloropentyl)zinc solution
EINECS	Contact for details

Quality Control

Every batch of 5-Chloropentylzinc Bromide is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as concentration, active zinc content, and impurity profile. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards, supporting applications from research to commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. This material is both hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For optimal stability, maintain at recommended temperatures between 2°C and 8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, oxidizing agents, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (Typical)	0.5 M in Tetrahydrofuran (THF)
Assay (Active Zn)	≥ 95% (by Titration)
Identification (NMR)	Conforms to structure
Water Content (Karl Fischer)	≤ 100 ppm
Related Impurities (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.