Description

1-Adamantylzinc Bromide is a highly reactive organozinc reagent featuring the rigid, three-dimensional adamantyl group. This compound matters as a versatile building block for introducing the bulky, lipophilic adamantyl moiety into complex molecular architectures, which is valuable for modifying physical and pharmacological properties. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions and the synthesis of novel chemical entities.

Application

• Key intermediate in Negishi cross-coupling reactions for C-C bond formation.
• Synthesis of adamantane-substituted active pharmaceutical ingredients (APIs) and drug candidates.
• Preparation of specialty ligands and catalysts for asymmetric synthesis.
• Building block for advanced organic materials with enhanced thermal stability.
• Introduction of the adamantyl group into agrochemical compounds to alter bioavailability and stability.
• Research and development of novel chemical entities in medicinal chemistry.

Basic Information

Product Name	1-Adamantylzinc Bromide
CAS No.	312624-15-0
Molecular Formula	C10H15BrZn
Molecular Weight	280.53 g/mol
Synonyms	Adamantan-1-ylzinc Bromide; Zinc, bromo(1-adamantyl)-; (1-Adamantyl)zinc Bromide; 1-Adamantyl Zinc Bromide; Bromo(adamantan-1-yl)zinc; Adamantylzinc Bromide Solution
EINECS	Contact for details

Quality Control

Our 1-Adamantylzinc Bromide is produced and handled under stringent quality systems. Each batch undergoes rigorous analytical testing to ensure consistency and high purity, typically specified as a solution in tetrahydrofuran or other suitable solvents. Certificates of Analysis (COA) detailing concentration, identity, and impurity profiles are available upon request to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly moisture-sensitive (hygroscopic) and pyrophoric nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures of 2-8°C. Handle only in a certified fume hood using appropriate techniques for air-sensitive materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (NMR/IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.