Description

3-Chlorobenzylzinc Chloride is an organozinc reagent, specifically a benzylzinc halide, widely used as a key building block in organic synthesis. This compound matters for its ability to introduce the 3-chlorobenzyl group into target molecules via cross-coupling reactions, enabling the efficient construction of complex chemical architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A crucial reagent for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates containing the 3-chlorobenzyl moiety.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the chlorinated benzyl group imparts specific biological activity.
• Cross-Coupling Reactions: Serves as a nucleophilic coupling partner in Negishi, Kumada, and related palladium-catalyzed cross-coupling reactions with aryl/vinyl halides.
• Ligand & Material Precursor: Employed in the development of specialized ligands for catalysis and as a monomer or precursor for advanced polymeric materials.
• Fine Chemical Manufacturing: Utilized in the multi-step synthesis of complex fine chemicals and specialty compounds for various industrial applications.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new synthetic pathways in research laboratories.

Basic Information

Product Name	3-Chlorobenzylzinc Chloride
CAS No.	312624-13-8
Molecular Formula	C7H6Cl2Zn
Molecular Weight	226.39 g/mol
Synonyms	(3-Chlorobenzyl)zinc chloride; Zinc, chloromethyl-3-chlorophenyl-; 1-(Chlorozinciomethyl)-3-chlorobenzene; 3-Chlorobenzylzinc chloride solution; m-Chlorobenzylzinc chloride; (3-Chlorophenyl)methylzinc chloride; Benzene, 1-(chlorozinciomethyl)-3-chloro-
EINECS	Contact for details

Quality Control

Our 3-Chlorobenzylzinc Chloride is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure consistency, purity, and performance in sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, concentration (typically provided as a solution in THF or ether), and impurity profile is provided with every shipment to guarantee reliable and reproducible results for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, maintain at recommended temperatures (typically 2-8°C or as specified) and ensure the integrity of the septum-sealed container to prevent solvent evaporation and reagent degradation.

Specification

Item	Specification
Appearance (Solution)	Colorless to pale yellow solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.