Description

1-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrole-2-Carbaldehyde is a high-value, multi-functional heterocyclic building block characterized by its pyrrole core and trifluoromethylphenyl substituent. This compound is essential for advanced organic synthesis, offering a versatile aldehyde group for condensation reactions and a unique fluorinated aromatic system that can enhance the biological activity and physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials due to its conjugated system and fluorine content.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, to create more complex biaryl structures.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the influence of the ortho-trifluoromethyl group on reaction kinetics and molecular conformation.

Basic Information

Product Name	1-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrole-2-Carbaldehyde
CAS No.	312303-90-5
Molecular Formula	C12H8F3NO
Molecular Weight	239.19 g/mol
Synonyms	2-Formyl-1-[2-(trifluoromethyl)phenyl]pyrrole; 1H-Pyrrole-2-carboxaldehyde, 1-[2-(trifluoromethyl)phenyl]-; 1-(2-Trifluoromethylphenyl)-1H-pyrrole-2-carbaldehyde; α-Formyl-1-(2-trifluoromethylphenyl)pyrrole; 2-(2-Trifluoromethylphenyl)pyrrole-1-carbaldehyde; 312303-90-5; Pyrrole-2-carbaldehyde derivative (with 2-CF3-Ph)
EINECS	Contact for details

Quality Control

Our production of 1-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrole-2-Carbaldehyde adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.