Description

Cyclopentanecarboxylic Acid, 2-Isothiocyanato-, Ethyl Ester, (1R,2R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its core value lies in the reactive isothiocyanate functional group, which enables the efficient construction of thiourea and heterocyclic scaffolds under mild conditions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands, organocatalysts, and metal complexes for asymmetric catalysis.
• Chemical Biology Probe Synthesis: Employed to create isothiocyanate-functionalized probes for labeling and studying biological targets.
• Advanced Material Research: A building block for novel polymers or functional materials requiring specific spatial orientation of functional groups.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, stereochemically pure intermediates.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Isothiocyanato-, Ethyl Ester, (1R,2R)-Rel- (9Ci)
CAS No.	311341-95-4
Molecular Formula	C9H13NO2S
Molecular Weight	199.27 g/mol
Synonyms	(1R,2R)-rel-2-Isothiocyanatocyclopentanecarboxylic Acid Ethyl Ester; Ethyl (1R,2R)-rel-2-Isothiocyanatocyclopentanecarboxylate; rel-(1R,2R)-Ethyl 2-Isothiocyanatocyclopentanecarboxylate; 2-Isothiocyanatocyclopentanecarboxylic Acid Ethyl Ester, (1R,2R)-rel-; Cyclopentanecarboxylic acid, 2-isothiocyanato-, ethyl ester, (1R,2R)-rel-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to a quality management system suitable for supplying fine chemicals to regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.