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Dimethylammoniumdichlorotri(Mu-Chloro)Bis[(S)-(-)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Diruthenate(Ii) CAS NO 309735-86-2
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CAS No.:309735-86-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Dimethylammoniumdichlorotri(Mu-Chloro)Bis[(S)-(-)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Diruthenate(Ii) is a sophisticated chiral ruthenium complex designed for high-performance asymmetric catalysis. This compound matters because it provides exceptional enantioselectivity and catalytic activity for challenging synthetic transformations, enabling the production of optically pure intermediates. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals.
Application
- Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines.
- Pharmaceutical Intermediate Synthesis: Critical for constructing chiral centers in complex drug molecules and APIs with high optical purity.
- Fine Chemical Manufacturing: Used in the production of specialty aromas, flavors, and agrochemicals requiring specific stereochemistry.
- Methodology Development: A valuable tool for academic and industrial research in developing new catalytic asymmetric reactions.
- Process Chemistry Optimization: Employed to scale up efficient and selective synthetic routes from laboratory to pilot plant and production.
Basic Information
| Item | Details |
|---|---|
| Product Name | Dimethylammoniumdichlorotri(Mu-Chloro)Bis[(S)-(-)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Diruthenate(Ii) |
| CAS No. | 309735-86-2 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | [(S)-(-)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl]ruthenium complex; (S)-Ru-Tol-BINAP complex; Diruthenium dichloride BINAP derivative; Asymmetric hydrogenation catalyst Ru(S)-TolBINAP; Chiral ruthenium phosphine catalyst; (S)-DTBM-SEGPHOS-Ru complex (related analog); (S)-BINAP-RuCl2 dimethylammonium salt |
| EINECS | Contact for details |
Quality Control
Every batch of our chiral catalyst is produced and tested under strict quality management protocols to ensure consistent high performance and enantiomeric excess (ee). We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as purity, chiral purity, and metal content. Our quality systems support development under cGMP guidelines where required for pharmaceutical applications.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C to maintain stability. This material is hygroscopic and easily oxidized; therefore, containers must be sealed immediately after use to minimize exposure to moisture and air.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to brown solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Ruthenium Content | Contact for details |
| Solubility | Soluble in common organic solvents (DCM, THF, toluene) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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