Description

4-(Boc-Amidino)-Benzaldehyde is a protected benzaldehyde derivative featuring a tert-butoxycarbonyl (Boc)-protected amidine functional group. This compound serves as a versatile and critical building block in organic synthesis, particularly for the controlled introduction of amidine moieties into target molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of protease inhibitors, kinase inhibitors, and other bioactive molecules containing amidine functionalities.
• Peptidomimetic Chemistry: Used in the construction of peptide analogs and mimetics where the Boc-protected amidino-benzaldehyde acts as a side-chain or backbone modifier.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers and functional materials.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry and the development of chemical tools.
• Academic Research: Employed in methodological studies and the discovery of new synthetic routes involving protected amidines.

Basic Information

Product Name	4-(Boc-Amidino)-Benzaldehyde
CAS No.	308845-84-3
Molecular Formula	C₁₃H₁₆N₂O₃
Molecular Weight	248.28 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amidino]benzaldehyde; 4-[(tert-Butoxycarbonylamino)iminomethyl]benzaldehyde; 4-(N-Boc-amidino)benzaldehyde; 4-Formyl-N-Boc-benzamidine; p-(Boc-Amidino)benzaldehyde; 4-[(tert-Butoxycarbonyl)amino]iminomethyl]benzaldehyde; Benzaldehyde, 4-[(1,1-dimethylethoxy)carbonyl]amidino]-; 4-Carbamimidoylbenzaldehyde tert-butyl carbonate
EINECS	Contact for details

Quality Control

Our 4-(Boc-Amidino)-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials. For long-term storage, consider storage at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.