Description

2,2,2-Trifluoro-n-[4-(1-Piperidinylsulfonyl)Phenyl]Acetamide is a high-purity, specialized trifluoroacetamide derivative featuring a piperidinylsulfonylphenyl moiety, making it a valuable synthetic intermediate. Its core value proposition lies in its role as a key building block for the development of novel pharmaceutical compounds and advanced agrochemicals, where its unique fluorine and sulfonamide groups are critical for modulating biological activity and physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with enhanced potency and selectivity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and inflammation.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and sulfonamide groups contribute to improved efficacy and environmental profile.
• Chemical Biology Probe Synthesis: Employed in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor-ligand interactions in drug discovery.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique surface properties, thermal stability, or chemical resistance.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific R&D programs.

Basic Information

Product Name	2,2,2-Trifluoro-n-[4-(1-Piperidinylsulfonyl)Phenyl]Acetamide
CAS No.	308293-88-1
Molecular Formula	C13H15F3N2O3S
Molecular Weight	336.33 g/mol
Synonyms	N-[4-(1-Piperidinylsulfonyl)phenyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[4-(piperidin-1-ylsulfonyl)phenyl]acetamide; 4-(1-Piperidinosulfonyl)phenyltrifluoroacetamide; 308293-88-1; Trifluoroacetamide, N-[4-(1-piperidinylsulfonyl)phenyl]-; N-(4-(Piperidine-1-sulfonyl)phenyl)-2,2,2-trifluoroacetamide
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-[4-(1-Piperidinylsulfonyl)Phenyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.